The development of Gonadotropin releasing hormone-1 GnRH neurons is important for a functional reproduction system in vertebrates. From their origin in the nasal placode, GnRH neurons migrate along the olfactory-derived vomeronasal axons to the nasal forebrain junction and then turn caudally into the developing forebrain. Although research on the origin of GnRH neurons, their migration and genes associated with KS has identified multiple factors that influence development of this system, several aspects still remain unclear. Unraveling how specialized neurons arise from heterogenous cell populations and then migrate to their appropriate location has important implications for understanding the development and progression of neuronal disorders.
Nasal Placode Development, GnRH Neuronal Migration and Kallmann Syndrome
Glossary on youth
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Glossary on youth
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REF: Chisholm, L. Defined in Article 9 of The Convention on the Rights of Persons with Disabilities CRPD , accessibility is perceived through enabling persons with disabilities to live independently and participate fully in all aspects of life. For this purpose, authorities shall take appropriate measures to ensure to persons with disabilities access, on an equal basis with others, to the physical environment, to transportation, to information and communication, including information and communication technologies and systems, and to other facilities and services open or provided to the public, both in urban and in rural areas. These measures, which shall include the identification and elimination of obstacles and barriers to accessibility, shall apply, inter alia - both to the physical infrastructure but also to information, communication and other services - including electronic services and emergency services. Formally or socially recognised authorities or instances accredit courses, activities and their outcomes.